Vhf10002 details

Gene vhfRNAi AccessionVhf10002
Gene SymbolPCGF5
Gene DescriptionPolycomb group RING finger protein 5 (RING finger protein 159)
Gene Name in PaperPCGF5
GroupHost Factor
Ensembl Gene IDENST00000336126 ENST00000543648 ENST00000614189 
UniProt IDQ86SE9
Entrez Gene ID84333
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)