Vhf09996 details

Gene vhfRNAi AccessionVhf09996
Gene SymbolTP4A3
Gene DescriptionProtein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Gene Name in PaperTP4A3
GroupHost Factor
Ensembl Gene IDENST00000329397 ENST00000349124 ENST00000520105 ENST00000521578 ENST00000614325 ENST00000622569 ENST00000633518 ENST00000633621 
UniProt IDO75365
Entrez Gene ID11156
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)