RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf09992 |
Gene Symbol | SUN2 | |
Gene Description | SUN domain-containing protein 2 (Protein unc-84 homolog B) (Rab5-interacting protein) (Rab5IP) (Sad1/unc-84 protein-like 2) | |
Gene Name in Paper | SUN2 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000405018 ENST00000405510 ENST00000406622 | |
UniProt ID | Q9UH99 | |
Entrez Gene ID | 25777 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |