Vhf09962 details

Gene vhfRNAi AccessionVhf09962
Gene SymbolZN618
Gene DescriptionZinc finger protein 618
Gene Name in PaperZN618
GroupHost Factor
Ensembl Gene IDENST00000288466 ENST00000374126 ENST00000615615 
UniProt IDQ5T7W0
Entrez Gene ID114991
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)