Vhf09945 details

Gene vhfRNAi AccessionVhf09945
Gene SymbolRAE1L
Gene DescriptionmRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41)
Gene Name in PaperRAE1L
GroupHost Factor
Ensembl Gene IDENST00000371242 ENST00000395840 ENST00000395841 
UniProt IDP78406
Entrez Gene ID8480
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)