RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf09940 |
| Gene Symbol | CLYBL | |
| Gene Description | Citrate lyase subunit beta-like protein, mitochondrial (Citrate lyase beta-like) (Beta-methylmalate synthase) (EC 2.3.3.-) (Malate synthase) (EC 2.3.3.9) | |
| Gene Name in Paper | CLYBL | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000339105 ENST00000376354 ENST00000376355 | |
| UniProt ID | Q8N0X4 | |
| Entrez Gene ID | 171425 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |