vhfRNAi | RNAi screen analysis of viral host factors

Vhf09929 details

Gene	vhfRNAi Accession	Vhf09929
	Gene Symbol	LST1
	Gene Description	Leukocyte-specific transcript 1 protein (Protein B144)
	Gene Name in Paper	LST1
	Group	Host Factor
	Ensembl Gene ID	ENST00000303757 ENST00000339530 ENST00000376086 ENST00000376089 ENST00000376092 ENST00000376093 ENST00000376096 ENST00000376110 ENST00000383480 ENST00000383482 ENST00000383484 ENST00000383486 ENST00000400250 ENST00000400257 ENST00000400262 ENST00000400263 ENST00000400264 ENST00000400265 ENST00000411490 ENST00000412041 ENST00000412623 ENST00000413426 ENST00000414266 ENST00000415419 ENST00000415490 ENST00000415781 ENST00000417428 ENST00000418507 ENST00000420157 ENST00000420333 ENST00000420676 ENST00000420785 ENST00000420797 ENST00000422035 ENST00000422533 ENST00000423107 ENST00000423871 ENST00000425760 ENST00000426938 ENST00000427186 ENST00000427507 ENST00000428227 ENST00000428405 ENST00000428898 ENST00000429874 ENST00000429910 ENST00000430632 ENST00000430680 ENST00000430997 ENST00000432009 ENST00000432164 ENST00000433004 ENST00000433305 ENST00000433676 ENST00000434314 ENST00000436037 ENST00000436185 ENST00000437137 ENST00000437436 ENST00000437812 ENST00000438075 ENST00000438335 ENST00000438349 ENST00000438381 ENST00000440242 ENST00000440253 ENST00000440323 ENST00000440328 ENST00000442052 ENST00000443340 ENST00000443655 ENST00000443741 ENST00000446239 ENST00000447141 ENST00000447391 ENST00000448236 ENST00000448441 ENST00000449236 ENST00000449273 ENST00000450291 ENST00000450425 ENST00000451641 ENST00000451922 ENST00000452169 ENST00000453995 ENST00000454168 ENST00000455003 ENST00000455052 ENST00000455426 ENST00000455493 ENST00000455655 ENST00000455901 ENST00000457549 ENST00000458456
	UniProt ID	O00453
	Entrez Gene ID	7940
	GO	View
Host	Organism	Homo sapiens
Virus	Virus full name	Poliovirus
	Virus Abbreviation	PV
	Taxonomy	View
Results	Phenotype	Increased infection
	Hits Number*	124
	Confirmed Hits Number	27
	Score	NA
	Unit	NA
Methods	Assay Type	Cell-based
	BioModel Description	HEp-2C and Vero cells
	Confirmatory Screen Description	ELISA
	Primary Screen Description^#	Z-score of ≥ 3.0
	Note/Comment	A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References	Pubmed ID	26581994

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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)

For any queries contact: Dr. Manoj Kumar