RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf09881 |
| Gene Symbol | AGRL2 | |
| Gene Description | Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin homolog 1) (Latrophilin-2) (Lectomedin-1) | |
| Gene Name in Paper | AGRL2 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000319517 ENST00000359929 ENST00000370713 ENST00000370715 ENST00000370717 ENST00000370723 ENST00000370725 ENST00000370728 ENST00000370730 | |
| UniProt ID | O95490 | |
| Entrez Gene ID | 23266 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |