RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf09878 |
| Gene Symbol | VGFR1 | |
| Gene Description | Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor) | |
| Gene Name in Paper | VGFR1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000282397 ENST00000539099 ENST00000541932 ENST00000543394 ENST00000615840 | |
| UniProt ID | P17948 | |
| Entrez Gene ID | 2321 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |