RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf09873 |
Gene Symbol | CK5P3 | |
Gene Description | CDK5 regulatory subunit-associated protein 3 (CDK5 activator-binding protein C53) (LXXLL/leucine-zipper-containing ARF-binding protein) (Protein HSF-27) | |
Gene Name in Paper | CK5P3 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000338399 ENST00000536708 | |
UniProt ID | Q96JB5 | |
Entrez Gene ID | 80279 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |