Vhf09869 details

Gene vhfRNAi AccessionVhf09869
Gene SymbolCE170
Gene DescriptionCentrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene Name in PaperCE170
GroupHost Factor
Ensembl Gene IDENST00000366542 ENST00000366543 ENST00000366544 ENST00000450306 ENST00000612450 ENST00000621831 
UniProt IDQ5SW79
Entrez Gene ID9859
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)