RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf09860 |
| Gene Symbol | DXO | |
| Gene Description | Decapping and exoribonuclease protein (DXO) (EC 3.1.13.-) (EC 3.6.1.-) (Dom-3 homolog Z) | |
| Gene Name in Paper | DXO | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000337523 ENST00000375349 ENST00000375356 ENST00000383330 ENST00000399936 ENST00000399937 ENST00000414092 ENST00000419797 ENST00000426498 ENST00000427627 ENST00000427690 ENST00000432110 ENST00000439989 ENST00000443250 ENST00000446967 ENST00000453742 ENST00000454430 ENST00000458308 | |
| UniProt ID | O77932 | |
| Entrez Gene ID | 1797 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |