RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf09840 |
| Gene Symbol | SEN34 | |
| Gene Description | tRNA-splicing endonuclease subunit Sen34 (EC 4.6.1.16) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34) | |
| Gene Name in Paper | SEN34 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000302937 ENST00000396383 ENST00000396388 ENST00000611560 ENST00000611798 ENST00000612236 ENST00000612393 ENST00000613310 ENST00000613712 ENST00000613888 ENST00000614948 ENST00000614984 ENST00000615000 ENST00000615079 ENST00000615900 ENST00000615975 ENST00000616063 ENST00000616209 ENST00000617149 ENST00000617902 ENST00000618135 ENST00000619994 ENST00000622524 ENST00000622538 | |
| UniProt ID | Q9BSV6 | |
| Entrez Gene ID | 79042 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |