Vhf09839 details

Gene vhfRNAi AccessionVhf09839
Gene SymbolBRD1
Gene DescriptionBromodomain-containing protein 1 (BR140-like protein) (Bromodomain and PHD finger-containing protein 2)
Gene Name in PaperBRD1
GroupHost Factor
Ensembl Gene IDENST00000216267 ENST00000404034 ENST00000404760 ENST00000457780 
UniProt IDO95696
Entrez Gene ID23774
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)