RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf09830 |
Gene Symbol | TWF2 | |
Gene Description | Twinfilin-2 (A6-related protein) (hA6RP) (Protein tyrosine kinase 9-like) (Twinfilin-1-like protein) | |
Gene Name in Paper | TWF2 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000305533 | |
UniProt ID | Q6IBS0 | |
Entrez Gene ID | 11344 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |