RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf09780 |
Gene Symbol | TF7L2 | |
Gene Description | Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4) | |
Gene Name in Paper | TF7L2 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000352065 ENST00000355717 ENST00000355995 ENST00000369397 ENST00000538897 ENST00000627217 | |
UniProt ID | Q9NQB0 | |
Entrez Gene ID | 6934 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |