RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf09778 |
Gene Symbol | TRPC4 | |
Gene Description | Short transient receptor potential channel 4 (TrpC4) (Trp-related protein 4) (hTrp-4) (hTrp4) | |
Gene Name in Paper | TRPC4 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000338947 ENST00000355779 ENST00000358477 ENST00000379673 ENST00000379679 ENST00000379705 ENST00000488717 ENST00000625583 | |
UniProt ID | Q9UBN4 | |
Entrez Gene ID | 7223 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |