Vhf09767 details

Gene vhfRNAi AccessionVhf09767
Gene SymbolACBP
Gene DescriptionAcyl-CoA-binding protein (ACBP) (Diazepam-binding inhibitor) (DBI) (Endozepine) (EP)
Gene Name in PaperACBP
GroupHost Factor
Ensembl Gene IDENST00000311521 ENST00000355857 ENST00000393103 ENST00000409094 ENST00000535757 ENST00000627093 ENST00000627305 
UniProt IDP07108
Entrez Gene ID1622
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)