Vhf09762 details

Gene vhfRNAi AccessionVhf09762
Gene SymbolGLRB
Gene DescriptionGlycine receptor subunit beta (Glycine receptor 58 kDa subunit)
Gene Name in PaperGLRB
GroupHost Factor
Ensembl Gene IDENST00000264428 ENST00000509282 ENST00000541722 
UniProt IDP48167
Entrez Gene ID2743
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)