Vhf09727 details

Gene vhfRNAi AccessionVhf09727
Gene SymbolANKR6
Gene DescriptionAnkyrin repeat domain-containing protein 6 (Diversin)
Gene Name in PaperANKR6
GroupHost Factor
Ensembl Gene IDENST00000339746 ENST00000369408 ENST00000447838 ENST00000520793 ENST00000522441 
UniProt IDQ9Y2G4
Entrez Gene ID22881
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)