Vhf09705 details

Gene vhfRNAi AccessionVhf09705
Gene SymbolKR251
Gene DescriptionKeratin-associated protein 25-1
Gene Name in PaperKR251
GroupHost Factor
Ensembl Gene IDENST00000416044 
UniProt IDQ3LHN0
Entrez Gene ID100131902
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)