Vhf09684 details

Gene vhfRNAi AccessionVhf09684
Gene SymbolSLC31
Gene DescriptionNeutral and basic amino acid transport protein rBAT (NBAT) (D2h) (Solute carrier family 3 member 1) (b(0,+)-type amino acid transport protein)
Gene Name in PaperSLC31
GroupHost Factor
Ensembl Gene IDENST00000260649 ENST00000409229 ENST00000409380 ENST00000409740 ENST00000409741 ENST00000410056 
UniProt IDQ07837
Entrez Gene ID6519
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)