Vhf09624 details

Gene vhfRNAi AccessionVhf09624
Gene SymbolBAALC
Gene DescriptionBrain and acute leukemia cytoplasmic protein
Gene Name in PaperBAALC
GroupHost Factor
Ensembl Gene IDENST00000297574 ENST00000306391 ENST00000309982 ENST00000330955 ENST00000438105 
UniProt IDQ8WXS3
Entrez Gene ID79870
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)