RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf09621 |
| Gene Symbol | TNR6 | |
| Gene Description | Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95) | |
| Gene Name in Paper | TNR6 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000355279 ENST00000355740 ENST00000357339 ENST00000479522 ENST00000484444 ENST00000488877 ENST00000492756 ENST00000494410 | |
| UniProt ID | P25445 | |
| Entrez Gene ID | 355 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |