RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf09610 |
Gene Symbol | DLP1 | |
Gene Description | Decaprenyl-diphosphate synthase subunit 2 (EC 2.5.1.91) (All-trans-decaprenyl-diphosphate synthase subunit 2) (Candidate tumor suppressor protein) (Decaprenyl pyrophosphate synthase subunit 2) | |
Gene Name in Paper | DLP1 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000369031 ENST00000369037 | |
UniProt ID | Q86YH6 | |
Entrez Gene ID | 57107 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |