Vhf09600 details

Gene vhfRNAi AccessionVhf09600
Gene SymbolZN266
Gene DescriptionZinc finger protein 266 (Zinc finger protein HZF1)
Gene Name in PaperZN266
GroupHost Factor
Ensembl Gene IDENST00000588221 ENST00000588933 ENST00000590306 ENST00000592292 ENST00000592904 
UniProt IDQ14584
Entrez Gene ID10781
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)