Vhf09588 details

Gene vhfRNAi AccessionVhf09588
Gene SymbolSC23B
Gene DescriptionProtein transport protein Sec23B (SEC23-related protein B)
Gene Name in PaperSC23B
GroupHost Factor
Ensembl Gene IDENST00000262544 ENST00000336714 ENST00000377465 ENST00000377475 
UniProt IDQ15437
Entrez Gene ID10483
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)