Vhf09579 details

Gene vhfRNAi AccessionVhf09579
Gene SymbolTAXB1
Gene DescriptionTax1-binding protein 1 (TRAF6-binding protein)
Gene Name in PaperTAXB1
GroupHost Factor
Ensembl Gene IDENST00000265393 ENST00000396319 ENST00000433216 ENST00000543117 
UniProt IDQ86VP1
Entrez Gene ID8887
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)