RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf09576 |
| Gene Symbol | XBP1 | |
| Gene Description | X-box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5) (TREB-5) [Cleaved into: X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form] | |
| Gene Name in Paper | XBP1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000216037 ENST00000344347 ENST00000611155 | |
| UniProt ID | P17861 | |
| Entrez Gene ID | 7494 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |