RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf09563 |
| Gene Symbol | EHMT2 | |
| Gene Description | Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.43) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a) | |
| Gene Name in Paper | EHMT2 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000375530 ENST00000375537 ENST00000383372 ENST00000383373 ENST00000420336 ENST00000420874 ENST00000421926 ENST00000429506 ENST00000450075 ENST00000450229 | |
| UniProt ID | Q96KQ7 | |
| Entrez Gene ID | 10919 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |