Vhf09504 details

Gene vhfRNAi AccessionVhf09504
Gene SymbolMEF2C
Gene DescriptionMyocyte-specific enhancer factor 2C
Gene Name in PaperMEF2C
GroupHost Factor
Ensembl Gene IDENST00000340208 ENST00000424173 ENST00000437473 ENST00000504921 ENST00000508569 ENST00000514015 ENST00000514028 ENST00000625674 ENST00000628656 ENST00000629612 
UniProt IDQ06413
Entrez Gene ID4208
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)