Vhf09503 details

Gene vhfRNAi AccessionVhf09503
Gene SymbolETV5
Gene DescriptionETS translocation variant 5 (Ets-related protein ERM)
Gene Name in PaperETV5
GroupHost Factor
Ensembl Gene IDENST00000306376 ENST00000434744 
UniProt IDP41161
Entrez Gene ID2119
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)