Vhf09495 details

Gene vhfRNAi AccessionVhf09495
Gene SymbolH4
Gene DescriptionHistone H4
Gene Name in PaperH4
GroupHost Factor
Ensembl Gene IDENST00000244537 ENST00000355057 ENST00000358064 ENST00000377727 ENST00000377745 ENST00000377803 ENST00000539745 ENST00000578186 ENST00000579512 ENST00000611927 ENST00000612061 ENST00000613412 ENST00000614247 ENST00000614272 ENST00000615164 ENST00000615353 ENST00000617569 ENST00000618193 ENST00000618305 ENST00000621520 ENST00000634560 ENST00000634956 ENST00000635491 
UniProt IDP62805
Entrez Gene ID121504;554313;8294;8359;8360;8361;8362;8363;8364;8365;8366;8367;8368;8370
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)