Vhf09438 details

Gene vhfRNAi AccessionVhf09438
Gene SymbolS52A3
Gene DescriptionSolute carrier family 52, riboflavin transporter, member 3 (Riboflavin transporter 2) (hRFT2)
Gene Name in PaperS52A3
GroupHost Factor
Ensembl Gene IDENST00000217254 ENST00000381944 ENST00000632431 
UniProt IDQ9NQ40
Entrez Gene ID113278
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)