Vhf09432 details

Gene vhfRNAi AccessionVhf09432
Gene SymbolTRI72
Gene DescriptionTripartite motif-containing protein 72 (Mitsugumin-53) (Mg53)
Gene Name in PaperTRI72
GroupHost Factor
Ensembl Gene IDENST00000322122 ENST00000613872 
UniProt IDQ6ZMU5
Entrez Gene ID493829
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)