Vhf09424 details

Gene vhfRNAi AccessionVhf09424
Gene SymbolSTAG2
Gene DescriptionCohesin subunit SA-2 (SCC3 homolog 2) (Stromal antigen 2)
Gene Name in PaperSTAG2
GroupHost Factor
Ensembl Gene IDENST00000218089 ENST00000371144 ENST00000371145 ENST00000371157 ENST00000371160 
UniProt IDQ8N3U4
Entrez Gene ID10735
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)