Vhf09419 details

Gene vhfRNAi AccessionVhf09419
Gene SymbolCOBA2
Gene DescriptionCollagen alpha-2(XI) chain
Gene Name in PaperCOBA2
GroupHost Factor
Ensembl Gene IDENST00000383087 ENST00000383088 ENST00000395194 ENST00000439039 ENST00000447741 ENST00000452937 ENST00000549811 ENST00000551542 
UniProt IDP13942
Entrez Gene ID1302
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)