RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf09418 |
Gene Symbol | P4HA2 | |
Gene Description | Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2) | |
Gene Name in Paper | P4HA2 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000166534 ENST00000360568 ENST00000379086 ENST00000379100 ENST00000379104 ENST00000401867 | |
UniProt ID | O15460 | |
Entrez Gene ID | 8974 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |