Vhf09404 details

Gene vhfRNAi AccessionVhf09404
Gene SymbolPHIPL
Gene DescriptionPhytanoyl-CoA hydroxylase-interacting protein-like
Gene Name in PaperPHIPL
GroupHost Factor
Ensembl Gene IDENST00000373878 ENST00000373880 ENST00000486074 
UniProt IDQ96FC7
Entrez Gene ID84457
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)