Vhf09394 details

Gene vhfRNAi AccessionVhf09394
Gene SymbolZN189
Gene DescriptionZinc finger protein 189
Gene Name in PaperZN189
GroupHost Factor
Ensembl Gene IDENST00000259395 ENST00000339664 ENST00000374861 
UniProt IDO75820
Entrez Gene ID7743
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)