Vhf09386 details

Gene vhfRNAi AccessionVhf09386
Gene SymbolLY66F
Gene DescriptionLymphocyte antigen 6 complex locus protein G6f
Gene Name in PaperLY66F
GroupHost Factor
Ensembl Gene IDENST00000375832 ENST00000383420 ENST00000442105 ENST00000446062 ENST00000447811 ENST00000453044 ENST00000455632 
UniProt IDQ5SQ64
Entrez Gene ID259215
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)