Vhf09385 details

Gene vhfRNAi AccessionVhf09385
Gene SymbolLY66D
Gene DescriptionLymphocyte antigen 6 complex locus protein G6d (Protein Ly6-D) (Megakaryocyte-enhanced gene transcript 1 protein)
Gene Name in PaperLY66D
GroupHost Factor
Ensembl Gene IDENST00000375825 ENST00000400080 ENST00000419389 ENST00000420378 ENST00000434515 ENST00000440095 ENST00000444880 
UniProt IDO95868
Entrez Gene ID58530
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)