RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf09385 |
Gene Symbol | LY66D | |
Gene Description | Lymphocyte antigen 6 complex locus protein G6d (Protein Ly6-D) (Megakaryocyte-enhanced gene transcript 1 protein) | |
Gene Name in Paper | LY66D | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000375825 ENST00000400080 ENST00000419389 ENST00000420378 ENST00000434515 ENST00000440095 ENST00000444880 | |
UniProt ID | O95868 | |
Entrez Gene ID | 58530 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |