Vhf09380 details

Gene vhfRNAi AccessionVhf09380
Gene SymbolTPGS2
Gene DescriptionTubulin polyglutamylase complex subunit 2 (PGs2)
Gene Name in PaperTPGS2
GroupHost Factor
Ensembl Gene IDENST00000334295 ENST00000383056 ENST00000589049 ENST00000590842 ENST00000593035 
UniProt IDQ68CL5
Entrez Gene ID25941
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)