Vhf09374 details

Gene vhfRNAi AccessionVhf09374
Gene SymbolRHG25
Gene DescriptionRho GTPase-activating protein 25 (Rho-type GTPase-activating protein 25)
Gene Name in PaperRHG25
GroupHost Factor
Ensembl Gene IDENST00000409030 ENST00000409202 ENST00000409220 ENST00000467265 ENST00000497079 
UniProt IDP42331
Entrez Gene ID9938
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)