RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf09372 |
| Gene Symbol | RFOX2 | |
| Gene Description | RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity) | |
| Gene Name in Paper | RFOX2 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000262829 ENST00000405409 ENST00000414461 ENST00000416721 ENST00000438146 ENST00000449924 ENST00000618140 ENST00000619768 ENST00000626107 ENST00000627946 ENST00000631365 | |
| UniProt ID | O43251 | |
| Entrez Gene ID | 23543 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |