Vhf09371 details

Gene vhfRNAi AccessionVhf09371
Gene SymbolT2R14
Gene DescriptionTaste receptor type 2 member 14 (T2R14) (Taste receptor family B member 1) (TRB1)
Gene Name in PaperT2R14
GroupHost Factor
Ensembl Gene IDENST00000537503 ENST00000575008 ENST00000614274 
UniProt IDQ9NYV8
Entrez Gene ID50840
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)