RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf09369 |
| Gene Symbol | NDRG1 | |
| Gene Description | Protein NDRG1 (Differentiation-related gene 1 protein) (DRG-1) (N-myc downstream-regulated gene 1 protein) (Nickel-specific induction protein Cap43) (Reducing agents and tunicamycin-responsive protein) (RTP) (Rit42) | |
| Gene Name in Paper | NDRG1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000323851 ENST00000414097 ENST00000522476 ENST00000537882 | |
| UniProt ID | Q92597 | |
| Entrez Gene ID | 10397 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |