Vhf09358 details

Gene vhfRNAi AccessionVhf09358
Gene SymbolLYG2
Gene DescriptionLysozyme g-like protein 2 (EC 3.2.1.-)
Gene Name in PaperLYG2
GroupHost Factor
Ensembl Gene IDENST00000333017 ENST00000409238 ENST00000423800 ENST00000626374 
UniProt IDQ86SG7
Entrez Gene ID254773
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)