Vhf09303 details

Gene vhfRNAi AccessionVhf09303
Gene SymbolBTNL8
Gene DescriptionButyrophilin-like protein 8
Gene Name in PaperBTNL8
GroupHost Factor
Ensembl Gene IDENST00000231229 ENST00000340184 ENST00000400707 ENST00000508408 ENST00000511704 ENST00000533815 ENST00000610640 
UniProt IDQ6UX41
Entrez Gene ID79908
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)