Vhf09302 details

Gene vhfRNAi AccessionVhf09302
Gene SymbolRM43
Gene Description39S ribosomal protein L43, mitochondrial (L43mt) (MRP-L43) (Mitochondrial ribosomal protein bMRP36a)
Gene Name in PaperRM43
GroupHost Factor
Ensembl Gene IDENST00000299179 ENST00000318325 ENST00000318364 ENST00000342071 ENST00000370234 ENST00000370236 ENST00000370242 
UniProt IDQ8N983
Entrez Gene ID84545
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)